Schizophrenia linked
Andhra Pradesh ~ India ~ International ~ City ~ Entertainment ~ Business ~ Sports ~ Technology ~ Health ~ Features
Breast Cancer ~ Swine Flu ~ Lung Cancer ~ Heart attack ~ Pregnancy ~ All Health Topics
Home / Health News / 2009 / July 2009 / July 9, 2009
Schizophrenia linked to specific DNA region
RSS / Print / Comments

Health News

New study confirms smoking, cancer link (reissue)
Taking up smoking results in epigenetic changes associated with the development of cancer, UK scientists have reported. ANI

Blame your mom for your muffin top or thunder thighs
A new study by an international team of researchers, including Cambridge and Oxford experts, has revealed that our propensity to be apple or pear-shaped is at least partly in our genes. ANI

Chemicals in mother's blood linked to child's obesity
A team of scientists has revealed that babies whose mothers had relatively high levels of the chemical DDE in their blood were more likely to both grow rapidly during their first 6 months and to have a high body ma*s index (BMI) by 14 months. ANI

Schizophrenia linked to specific DNA region

An international group of researchers have for the first time come up with genetic evidence linking schizophrenia to a specific region of DNA - on chromosome 6.

London, July 9 : An international group of researchers have for the first time come up with genetic evidence linking schizophrenia to a specific region of DNA - on chromosome 6.

Lead researcher Nancy Buccola, Assistant Professor of Clinical Nursing at LSU Health Sciences Center New Orleans, says that this is the same area where key genes for immune function are located.

The researchers recruited study participants, people with diagnoses of schizophrenia or schizoaffective disorder, as well as controls from the general population.

They analysed data collected and also conducted a meta-analysis of data from the Molecular Genetics of Schizophrenia, International Schizophrenia Consortium and SGENE data sets - thousands of DNA samples.

The team point out that while a single gene does not appear to be the source of the development of schizophrenia, variations on chromosome 6 appeared to be associated with higher risk.

According to them, these variations were found most often in people with schizophrenia, leading the scientists to believe that these common variations contribute to the development of schizophrenia.

They further said that the area of chromosome 6, in the same area where genes important to the immune system function, provokes questions about whether or not treatments for autoimmune disorders might also be helpful in treating schizophrenia.

"Schizophrenia can be a devastating disease, and while treatments are improving, there are still people who do not respond or only partially respond," Nature magazine quoted Buccola, principal investigator on the LSUHSC study, as noting.

"Understanding the underpinnings of this illness will open doors to new and potentially better treatments," the researcher added.

The research was supported by funding from the National Institute of Mental Health and the National Alliance for Research on Schizophrenia and Depression.

"Scientists have been looking for schizophrenia susceptibility genes since the early 1900s. This study shows that these genes can be found and sets the stage for future research," says Buccola.


Link to this page

Suggested pages for your additional reading on Facebook

© 2000-2017 All Rights Reserved and are of their respective owners.
Disclaimer, Terms of Service & Privacy Policy | Contact Us