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/ Health News / 2008 / September 2008 / September 4, 2008 Blood fingerprints can serve as biomarkers for cancer, diabetes |
Drug combo may help treat previously resistant tumours
Anti-tobacco ads should either scare or disgust viewers: Study
China Medical Technologies Completes the Development of EGFR Molecular Diagnostic Kits
How cancer prevention drives aging
For the first time, researchers have found how cellular senescence, the well-known mechanism for preventing cancer, can trigger aging and age-related disease by changing the local tissue environment. ANI
Scientists unveil genes vital to vital to adult heart function
In a study on fruit fly Drosophila, scientists at the Burnham Institute for Medical Research (Burnham) have found that genes involved in embryonic heart development are vital to adult heart function in both fruit flies and humans. ANI
Psychiatric disorders common among college-aged
A new study has revealed that psychiatric disorders appear to be common among 18- to 24-year-olds, with overall rates similar among those attending or not attending college. ANI
In a revolutionary discovery, scientists have found that Serum microRNAs (miRNAs) in the blood can act as efficient fingerprints for detecting diseases including cancer and diabetes, says a new research.
Washington, Sept 4 : In a revolutionary discovery, scientists have found that Serum microRNAs (miRNAs) in the blood can act as efficient 'fingerprints' for detecting diseases including cancer and diabetes, says a new research.
miRNAs are a class of naturally occurring small non-coding RNAs that have been linked with cancer development.
The finding can pave the way for an innovative non-invasive diagnostic tool.
According to recent studies, individual miRNAs as diagnostic biomarkers of specific cancers could not do away with the chances that these miRNAs appeared as a result of contamination.
Chen-Yu Zhang and colleagues are the first to comprehensively characterize entire blood miRNA profiles of healthy subjects and patients with lung cancer, colorectal cancer and diabetes, ruling out contamination.
They suggested that the specific serum miRNA expression profiles they identified make up for 'fingerprints' for cancer and disease.
While tumour markers do improve diagnosis to a large extent, current diagnostic techniques are prohibitively invasive and thus have limited clinical application.
The new approach is non-invasive and has the potential to transform the clinical management of various cancers and diseases through improving disease diagnosis, cancer classification, prognosis estimation, prediction of therapeutic efficacy, maintenance of surveillance following surgery, and the ability to forecast disease recurrence.
The technique will also be useful to pharmacological companies in identifying population subgroups who are responsive to drugs that have failed in phase III clinical trials.
The study is published online this week in Cell Research.
ANI
