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/ Health News / 2008 / November 2008 / November 20, 2008 Personalised cancer treatment on the anvil |
Longer sleep duration reduces incidence of coronary artery calcification
How little nano-machines inside the body operate
Racial prejudice costs black workers nearly $115,000 over their lifetime
Exercise may not be key to weight loss
Scientists uncover how metastatic cancer cells plan their relocation
`The whole three days have really blown me away, says emotional McGrath
Sack lunches may not provide adequate nutrients to preschooler
Packing lunch for your child might not be a good idea, for a new study has found that sack lunches may not regularly provide adequate nutrients for the growth and development of young children. ANI
Health-monitoring system helps maintain older adults well-being
Many older adults want to remain active and independent for as long as possible. Now, researchers from University of Missouri suggest that installing health monitoring system can help keep check on the health of the elderly and ensure their privacy. ANI
New drug shows potential to treat angina, other cardiac problems
A compound, designed to prevent chest pains in heart patients, could act as a drug to treat angina and possibly other cardiac pathologies, according to a study on animals. ANI
Researchers from University of Chicago have discovered a genetic signature that may help predict whether a patient will respond to cancer therapies - a finding that may pave way for personalised cancer treatment.
London, Nov 20 : Researchers from University of Chicago have discovered a genetic signature that may help predict whether a patient will respond to cancer therapies - a finding that may pave way for personalised cancer treatment.
The team led by Andy Minn at the University of Chicago have found that many cancers show abnormalities in 49 genes, collectively known as the IFN-related DNA damage resistance signature (IRDS).
After analysing 34 different cancer cell lines and several hundred primary human cancers, the researchers found that IRDS was linked to radiotherapy resistance.
However, in breast cancer patients, the genetic signature could correctly envisage which cancers would be resistant to chemotherapy.
"This moves us one step closer to personalising cancer treatment, and points towards ways to improve the effectiveness of chemotherapy and radiotherapy," New Scientists quoted a spokeswoman for Cancer Research UK (CRUK) as saying.
On the other hand, research team led by Jason Carroll at CRUK's Cambridge Research Institute found how breast cancers become resistant to the drug tamoxifen.
The team suggests that the new discovery may help in developing new drug and ways of predicting which patients are unlikely to respond to tamoxifen.
The new study appears in Proceedings of the National Academy of Sciences.
ANI
