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/ Health News / 2008 / August 2008 / August 19, 2008 Silencing disease-causing genes comes closer to reality |
Sack lunches may not provide adequate nutrients to preschooler
Packing lunch for your child might not be a good idea, for a new study has found that sack lunches may not regularly provide adequate nutrients for the growth and development of young children. ANI
Health-monitoring system helps maintain older adults well-being
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New drug shows potential to treat angina, other cardiac problems
A compound, designed to prevent chest pains in heart patients, could act as a drug to treat angina and possibly other cardiac pathologies, according to a study on animals. ANI
Mount Sinai researchers have developed a new technology that could be used to suppress genes, which lead to the development of certain diseases.
London, Aug 19 : Mount Sinai researchers have developed a new technology that could be used to suppress genes, which lead to the development of certain diseases.
According to researchers, this technology could pave the way for preventing diseases where gene dysfunction plays a role.
"By being able to silence certain genes, we may be able to suppress genes that can cause diseases such as HIV/AIDS, cancer, inflammation and diseases of the central and peripheral nervous systems," Nature quoted Ming-Ming Zhou, Ph.D., Professor and Chairman of the Department of Structural and Chemical Biology at Mount Sinai School of Medicine, as saying.
"We now know we can focus on these genes and potentially change the ultimate course of many diseases that have a major impact on people's lives," Dr. Zhou added.
In the study, Dr. Zhou and colleagues discovered that Paramecium bursaria chlorella virus uses a viral protein to modify host DNA packing chromatin and switch host transcription machinery for viral replication.
Based on this finding, researchers were able to develop a new gene targeting technology that effectively suppresses transcriptional expression of targeted genes in human cells, including genes that are linked to the onset of a number of diseases.
The findings are published in the September issue of Nature Cell Biology.
ANI
